Isixazululo Esigcwele Sezinkampani ze-IVD Zokusika Izindleko Eziphakeme Zokuluhlaza

I-DMT-dC(Bz)-CE Phosphoramidite (okujwayelekile) I-DMT-dG(i-Bu)-CE Phosphoramidite (okujwayelekile) I-DMT-dG(dmf)-CE Phosphoramidite (i-cleavage esheshayo) I-DMT-dT-CE Phosphoramidite I-DMT-dA(Bz)-CE Phosphoramidite

 

Emhlabeni wonke kufanele ubhekane nezindleko eziphezulu zezinto zokusetshenziswa, futhi kuthinta kakhulu i-IVD nezinye izinkampani kule mboni.

Ukusiza ngawo wonke amakhasimende akulesi simo, i-HonyaBiotech inesixazululo esigcwele somjikelezo we-Oligo synthesis sokukhiqizwa kwe-IVD feedstock.-I-HY-12 i-Synthesizer ephakathi nendawo, ngokwezifiso ezisekela izinsimbi ezizenzakalelayo ngokugcwele, i-Synthesis yekhwalithi ephezuluAmiditekanye ne-SynthesisAma-reagentskanye nezinsizakalo zokuqeqesha ezigcwele zokukhiqiza.

Ezinyangeni ezi-3, amanye amakhasimende ethu aphendula ngokuthi akwazi ukuqedela ukukhiqizwa kwawo kwe-IVD feedstock, anciphisa kakhulu izindleko zokukhiqiza, kuyilapho ethola isiqondiso esigcwele senqubo futhi ephendula ezindabeni zenqubo yokukhiqiza nganoma yisiphi isikhathi, ukonga isikhathi nezindleko.

 

未命名的设计(1)

 

 

Imikhawulo ye-solid-phase oligonucleotide synthesis

Nakuba ukwakheka kwe-DNA kusebenza kahle, ukungcola kuyanqwabelana ngokungenakugwenywa.Ukuhlanganiswa kwe-oligodeoxynucleotide engu-20mer kuhilela izinyathelo zamakhemikhali ezingazodwana ezingaphezu kwe-100, ngasinye esinamandla okusabela okungafuneki ohlangothini.Ngaphezu kokuqoqwa kwezingcezu ezihlulekile ezibangelwa ukuhlangana okungaphelele, ukunqunywa kweketango le-oligonucleotide ngemva kokucocwa kungase kukhiqize izingcezu zokugcina ezincishisiwe.

Ukuguqulwa kwamakhemikhali ama-base heterocycles ngezinye izikhathi kwenzeka, futhi imikhiqizo ye-oligonucleotide eshintshiwe ingase ibe ama-mutagens, angabangela kalula izinkinga ezinkulu ekuhloleni kwebhayoloji.Ngenxa yokuvela kokusabela okusemaceleni, ukuthola ama-oligonucleotide aphakeme kakhulu, kuyadingeka ukusebenzisa indlela engcono kakhulu yokuhlanza.


Isikhathi sokuthumela: Sep-06-2022